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by The Hemp Jubilation Team

March 8, 2021

Over the last few years, CBD-based products have grown rapidly in popularity thanks to their holistic and therapeutic properties. But there is a new up-and-coming cannabinoid known as Cannabigerol (CBG) that's attracting interest for having some medicinal benefits of its own. 

Both CBG and CBD are non-psychoactive which means they will not have the same ability to create a high the way THC will.

But, unlike CBD, however, little research has been performed on CBG, but the studies that are available suggest that it holds considerable therapeutic promise.

The CBG oil benefits according to resent studies are from high-quality sources, including peer-reviewed studies. 

What Is CBG?

CBG (cannabigerol) is one of the many organic compounds known as cannabinoids found in the cannabis plant. In most strains of the plant, only 1% of CBG can be found compared to 20 to 25% of CBD or up to 30% THC.

CBG stands out from the crowd of hemp-derived cannabinoids for one interesting reason.

It is known as the mother of all cannabinoids due to the fact that it is the precursor to all
other cannabinoids such as CBD (Cannabidiol), CBN (Cannabinol), CBC (Cannabichromene), and THCA (Tetrahydrocannabinolic Acid). Meaning, CBG is needed for us to even experience THC and CBD. 

It also activates both  CB1 and CB2 receptors  in the endocannabinoid system. This means it could possibly hold the cumulative qualities of all the other cannabinoids put together.

Read on to see the benefits of CBG, and much, much more. 

Potential Health Benefits Of CBG Oil?

While the research is still in the early stages, scientists have transitioned resources to focus on the power of CBG. Animal Studies thus far suggest that it offers several benefits.

CBG might ultimately be found useful for the following therapeutic benefits listed below.

A recent study on  CBG anti-inflammatory properties  suggests it can help limit excess lipogenesis and therefore prevent obesity.

CBG may also stimulate receptors that cause  nausea.

CBG May Reverse The Aging Process

One thing CBG stands out for is reducing inflammation and oxidative stress which is defined as an imbalance of free radicals and antioxidants in the body. Oxidative stress can damage cells, proteins, and DNA, which can contribute to  aging, and diseases,  including diabetes, cancer, inflammatory conditions, high blood pressure, heart disease, and neurodegenerative diseases.

Some of the most common conditions are Alzheimer’s and Parkinson's, Huntington’s disease, and Multiple Sclerosis. All neurodegenerative diseases are caused by the death of nerve cells in the brain and spinal cord, which leads to problems with balance, movement, talking, breathing, and/or mental function.

As people are living longer, an ever-increasing number are afflicted by these debilitating diseases. Neurodegeneration is now one of the major causes of preventing ones ability to carry on with regular activities and death. Sadly, there is no cure for these progressive diseases. But thankfully, cannabinoids, and notably CBG, are showing great promise for future potential therapies.

Antioxidant and Neuroprotective Effects of CBG

A recent  2020 study  was conducted to compare the Neuroinflammation efficacy of CBD and CBG. The study’s researchers say that CBD’s effectiveness against neurological diseases has already been demonstrated, so rodent experiments were carried out to measure the different roles that inflammation and oxidative stress played between the two cannabinoids’ effects.

The scientists conducted multiple tests to mimic the effects of neurological diseases on rat tissue. Both CBD and CBG proved effective, but, when brain and spinal cord cells were exposed to hydrogen peroxide-induced toxicity, “CBG was more potent than CBD in blunting neurotransmitter depletion,” the study concluded.

CBG was also more potent than CBD in counteracting toxicity in experiments done on rat cortexes.

Here are more links to specific studies on CBG

Parkinson’s Disease

 2018 study  on mice found that CBG offers neuroprotection against inflammation-driven neuronal damage .

Also a  2018 study  was carried out on CBG’s effect on neuroinflammation (that is defined as an inflammatory response within the brain or spinal cord). This in vitro study (that is defined as biological properties that are done in a test tube (i.e. in a glass vessel) rather than in a human or animal found CBG to be effective at reducing neuronal death, inflammation, and oxidative stress. meaning CBG restored cell anti-oxidant defense.

These results indicated the neuroprotective effects of CBG, that may be a potential treatment against neuroinflammation and oxidative stress.

Huntington’s Disease

Huntington’s disease is a rare and cruel hereditary disorder that progressively breaks down nerve cells in the brain.

Individuals with the disorder usually start to exhibit symptoms in their 30s or 40s and face physical, emotional, behavioral, and cognitive issues, and has symptoms that can be disruptive to everyday life.

Unfortunately there is no current cure for Huntington’s disease, however a promising  study on mice  with Huntington’s found that CBG was extremely active as a neuroprotectant. The study concluded that CBG could make it a potential treatment for a variety of neurodegenerative disorders as well.

Multiple Sclerosis

A  2014 study  in mice said that Phytocannabinoids (pCBs) that do not produce psychotropic effects, such as cannabidiol (CBD), cannabigerol (CBG), has been shown to alleviate symptoms in a viral model of multiple sclerosis.

Inflammatory Bowel Disease (IBD)

Inflammatory bowel disease is a condition that causes chronic inflammation of your digestive tract such as colitis and crohn's disease. It affects millions of people across the globe and is incurable.

CBG appears to reduce the inflammation associated with inflammatory bowel disease, according to an  animal study conducted in 2013.

Colon Cancer

Unsurprisingly, little research has looked at how CBG may help fight cancer. However, one study published in the PubMed journal Carcinogenesis,  did find that CBG might reduce the growth of cancer cells and other tumors in rats.

Gastrointestinal (GI) Cancer

In a  resent 2020 study,  Israeli researchers found that CBG and CBC (cannabichromene) exhibit anti-tumor properties as tested on human gastrointestinal (GI) cancer cells. Gastrointestinal (GI) cancer includes all cancers in your digestive tract organs such as the stomach, large and small intestine, pancreas, colon, liver, rectum, anus, and biliary system.

Bladder Dysfunctions

In a  2015 study  that investigated the effect of five different cannabinoids on bladder contractions, concluded that CBG shows the most promise at treating bladder dysfunctions.

Methicillin-resistant Staphylococcus aureus (MRSA)

This dangerous bacterial infection is infamous for its ability to resist most antibiotic treatments and nearly 120,000 people in the U.S. contracted MRSA, and almost 20,000 died. 

In a resent 2020 study researchers uncover hidden  antibiotic potential  of cannabis. CBG had the most promising activity against drug-resistant MRSA.

Anxiety 

Is CBG better than CBD for anxiety? The lesser-known CBG cannabinoid, is touted by cannabis advocates to be even more effective than CBD for anxiety.

Animal studies back the strong anti-anxiety effect of using CBG to reduce anxiety. As of yet there are no human studies on CBG. But one study in the  British Journal of Pharmacology  found that CBG had an analgesic effect on certain receptors, leading to anxiety reduction.

Appetite Stimulant

A study on rats in the PubMed journal Psychopharmacology  found that CBG is a reliable appetite stimulant. The rats in the study polished off more than doubled their normal food intake and ate extra meals while taking CBG. The appetite-boosting chemicals of CBG could be helpful for patients struggling to eat and maintain weight, such as individuals with HIV or cancer.

How to Take CBG

CBG Oil can be taken in a few different forms and delivery methods. There are usually benefits to each form of delivery, some providing faster absorption into the body than others. In general, taking this compound will be similar to CBD.

Just like CBD, oils and tinctures are the most common way to take CBG because it reaches the bloodstream more quickly. CBG, along with other cannabinoids, are extracted from hemp plants. Then, they’re mixed with a carrier oil (like MCT oil). 

How To Dose CBG

Unfortunately, there is no precise drop-by-drop instruction on how to properly dose CBG. Dosing CBD and CBG are personal from person to person as dosage can depend on a wide variety of factors, including: age, health, underlying conditions, tolerance, weight and desired results.

Only you can determine your ideal doses for CBG products. But the best rule of thumb is to start low and go slow, keep track of your experience in a journal, just like with CBD dosing.

Each brand will usually label in MG or a percentage of how much CBG is in the product. Always look for the product's recommended dose and start on the lower end of the spectrum and gradually build up until you reach your desired effects.

Keep in mind that taking CBG oil is a process that requires patience. This means that you shouldn’t expect to feel its effects after the first use. And consistency is key. Make sure to take your dose regularly.

How Does CBG Oil Make You Feel

The effects of CBG does not make you feel high. In fact quite the opposite, because it's known to counteract the paranoid and intense feelings that THC can make people feel.

According to  CBD American Shaman,  it's said to give a feeling of energy and focus that is similar to the effects of coffee. Some users report being able to focus on one task for longer periods of time, with increased levels of productivity.

Some users say the CBG is a pick-me-up. Overall, CBG effects on the senses level are more of an “upper” than a “downer.”

CBG can also help your digestive system continue to feel like it’s functioning properly. In addition, many users report mood support from consistent CBG usage.

CBG Side Effects

Unfortunately at this time very little is known about the side effects of CBG oil or other forms of CBG. So far, it seems to be  well tolerated by rats,  but there’s not enough research to say much about the potential side effects it might have on humans.

But keep in mind that just like any other medicine, vitamins or supplements, CBG can have side effects, if consumed in huge doses.

Does It Interact With Any Medications

Again not much is known about how CBG might interact with over-the-counter or prescription medications, as well as vitamins or supplements.

If you take any kind of medication, it’s best to check with your healthcare provider before trying any CBG product. 

CBG VS CBD

Although these two compounds have a lot in common, they also have some differences that make each one of them unique. As far as similarities are concerned, they both come from the cannabis plant and they both function in a similar fashion within the endocannabinoid system.

CBD molecules communicate with CB2 cannabinoid receptors and these receptors connect to the peripheral nervous system (PNS) which reaches various muscles, organs, skin, eyes, and other biological systems, including the immune system.

CBG on the other hand also attaches to CB2 receptors in addition to CB1 receptors, which connect to our central nervous system (CNS) that controls most functions of the body and mind.

CBD and CBG both offer beneficial attributes individually. They also work together to enhance each other’s benefits allowing for the entourage effect.

The entourage effect is a theory that could completely change how you decide to consume CBG going forward. 

The theory proposes the idea that CBG is more effective when it's ingested with other cannabinoids (the chemical compounds made by the cannabis plant that unlock its many healing powers)at the same time. 

And research and customer feedback have shown that results improve dramatically when cannabinoids are taken together.

Choosing a CBG product

Because CBG is newer to the market, way more expensive to extract than CBD, there aren't nearly as many products to choose from when compared to CBD. 

CBD users interested in taking CBG find that selecting a  full-spectrum or broad-spectrum  hemp-derived CBD products is best because they contain all the plant-based cannabinoids and terpenes including THC, CBD, CBG, and many others.

But, In full-spectrum CBD oils, CBG is typically found in quantities of less than 3%. This is a very small amount of CBG.

If you want the full effects of taking CBG, you should consider a  1:1 ratio of both CBG and CBD product to reap the benefits they both have to offer.

With that said, we've done some digging and found  7 Best CBG Oil Products Right Now (2021)  available to buy online, based on our own independent research, customer reviews, and lab test results. What's more, all of these options contain high amounts of CBG along with CBD, so both cannabinoids can work together to provide an array of potential holistic advantages.

Final Thoughts: CBG Oil Benefits

CBG is one of the lesser-known cannabinoids extracted from cannabis plants. This compound has been getting a lot of attention recently, thanks to its many potential health benefits. Several research findings from a variety of recent animal studies have reported CBG’s great potential.

Even though CBG may hold promise to its many potential effects, however,  the research around it is still pretty limited. So it’s important to note that more research is needed to support the above claims when it comes to human subjects.

And not much is known about its side effects or how it might interact with certain medications.

It is always recommended that you consult with your physician before you add it to your daily routine. Along with being advised on any potential drug interactions.


CBG Buyers Guide