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  • The 5 Best CBD Oil For Pain – Top Brands of 2021

Written by The Hemp Jubilation Team

Updated on: August 11, 2021

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The CBD oil that works best for you should meet your needs for pain relief, price point, and be safe. We’ll discuss our picks of the best CBD oil for pain, including unflavored and flavored, full-spectrum, broad-spectrum, Isolate, low potency and high potency oils.

Our best CBD oil for pain 2021 recommendations comes from reputable brands that have been third-party tested for safety and quality, are made from US-grown hemp, and have several positive reviews to backup the efficacy.

Let’s get started.

Our Picks of The Best CBD Oil for Pain

Relieving pain can help you return to your everyday life without the severe side effects that other prescribed medications may cause. And the best CBD oil for pain products below may help manage your pain, whether you have been feeling it for a long time or more recently.

Zatural Broad Spectrum CBD Oil Drops

Zatural is a family owned and run business started by Maryann Stanger, a naturopathic doctor. Stanger’s keen understanding of natural alternatives helped her create hemp products from the finest all-natural ingredients without harsh chemicals, fillers, or additives.

Best CBD oil for pain product image.


  • Type of CBD: Broad Spectrum
  • CBD potency: 10 mg CBD per serving
  • COA: Available on product page
  • Return Policy: 30-days 
  • Shipping: Free on all USA orders $5+

There is an assorted range of potencies from 300mg up to 3000mg! Along with several natural flavors to choose from, including natural flavor, sweet natural, peppermint, spearmint, cinnamon, and lemon-lime.

It also comes in three bottle sizes to choose from, including 1 ounce, 2 ounce, and 4 ounce.

Zatural sources all their hemp from non-GMO, organic hemp farms in Colorado. All their products are vegan-friendly and only uses two ingredients; hemp extract and hemp seed oil in their natural flavor CBD oils.

The company offers military and senior discounts to help make its products more affordable to these populations.

They also offer a subscription plan with repeat delivery options of 1, 2, 3, or 4 months and save 10% off your order. You can pause, skip or cancel anytime.

It also offers a wide range of affordable products that most reviewers seem to really love and almost all say that they work great, incredible quality product from a trusted company, cost efficient and great customer service. Some not so positive reviewers say the taste is overwhelming, leaves a bitter aftertaste, too early to tell if it's working.

Plant People Drops+ Mind + Body

Plant People delivers vegan, non-GMO, USDA organic, gluten free, cruelty free, FDA registered, Dr. Formulated, Clinical-Grade powerful CBD products.


  • Type of CBD: Full Spectrum
  • CBD potency: 21 mg CBD per serving
  • COA: Available on product page
  • Return Policy: 60-days 
  • Shipping: Free on all USA orders $60+

Available in a few strength options: 315mg 10.5mg per serving, 630mg 21mg per serving, and 1500mg 50mg per serving. Though the drops are unflavored, they do have a pleasant taste.

It’s made with three different cannabinoids including CBD, CBG, and CBL, along with terpenes, coconut MCT oil, and hempseed oil.

All of their hemp extracts is sourced from organic farms in Colorado. And According to their 3rd party test results available on product page, all of their products have passed their potency, heavy metal, residual solvents, pesticides, additive and pathogen tests. 

Created to calm the mind and body, this full-spectrum hemp extract is said to aid in inflammation and soothe daily aches and pains, and muscle recovery by supporting circulation and cell function.

The company offers a special Veterans discount for those who have served as a member of the United States military.

They also offer a subscription plan with repeat delivery options of 30 days, 60 days or 90 days, free shipping and save 15% off your order. You can pause, skip or cancel anytime.

The majority of reviewers say they love the products, pricing and quality are excellent, great customer service and fast shipping. The not so positive reviews are mostly about the taste being too strong and a few saying they don’t really feel anything yet.

Extract Labs CBD Tincture

Extract Labs is a safe, reputable and veteran-owned CBD company based in Boulder, Colorado. They offer quality, top-shelf CBD products at prices that are among the most affordable in the industry.

Best CBD oil for pain full-spectrum by Extract Labs.


  • Type of CBD: Full Spectrum
  • CBD potency: 33 mg CBD per serving
  • COA: Available on product page
  • Return Policy: 60-days 
  • Shipping: Free on all USA orders $50+

Extract Labs has an impressive product line of CBD tinctures. The options available are:

  • Pure CBD Isolate (2000mg)
  • Broad Spectrum Tincture (1000mg)
  • Original CBD Tincture (1000mg)
  • Original Strength CBD Tincture (2000mg)
  • Lemon CBD Tincture (1000mg)
  • Lemon Extra Strength CBD Tincture (2000mg)
  • Raspberry CBD Tincture (1000mg)
  • Raspberry Extra Strength CBD Tincture (2000mg)
  • Banana Foster CBD Tincture (1000mg)
  • Banana Foster Extra Strength CBD Tincture (2000mg)

All tinctures feature naturally occurring ingredients with no harmful chemicals, additives or artificial compounds. Each product is made from high-grade, American hemp that has been Organically-grown in Colorado and Kentucky.

One thing that stands out about this brand is occasionally, a CBD vetting company will have Extract Labs products tested by multiple 3rd-party labs, and guess what they find? They have been awarded the highest standards for perfect scores. One company (CBD Examine) went so far as to detail that per cannabinoid volume, it's tinctures are the best quality and value on the market.

This brand is committed to making CBD products more affordable to veterans, first responders, health care workers, teachers, disabled individuals and those with low income. They offer a 50% discount to those who qualify as part of their CBD Assistance Program.

Extract Labs reviews by real users are raving about the quality, great pricing and they say “a level of customer service unheard of in this day and age.” As far as not so positive reviews, there are none.

Use code "EXTRACT10" for 10% off sitewide

Nuleaf Naturals Full Spectrum CBD Oil

NuLeaf Naturals specializes in a whole-plant extract containing a full-spectrum CBD oil made from high-grade, organically-grown hemp extract. While other companies may have more variety in their line of CBD products, NuLeaf has been focused on producing what are known as some of the best CBD tinctures on the market.


  • Type of CBD: Full Spectrum
  • CBD potency: 30 mg CBD per serving
  • COA: Available on product page
  • Return Policy: 30-days 
  • Shipping: Free on all USA orders 

The CBD oils are available in a variety of bottle sizes ranging from 300mg of CBD in a 5ml bottle to 6000mg of CBD in a 100ml bottle. All bottles have the same high-potency formulation with 30mg of CBD per serving.

Based on independent lab test results, NuLeaf Naturals CBD oils have an impressive array of cannabinoids including CBD, THC, CBG, CBC and CBDA. They also have an abundance of terpenes including beta-caryophyllene. Researchers found positive effects in hemp strains rich in caryophyllene seem better at pain reduction and help with painful inflammations.

Along with all products are free of pesticides, herbicides, mold, fungi, heavy metals, and mycotoxins.

The brand has an impressive assistance programs for veterans, first responders, health care workers, teachers and students, non-profit groups and organizations, disabled individuals and those with low income.

They also offer a subscription plan with repeat delivery options of every 2, 4, 6, 8, or 12 weeks and save 10% off your order. You can pause, skip or cancel anytime.

Nuleaf Naturals reviews by real users and there are thousands of them on the company’s website — say that these help with pain and stiffness, anxiety, and also help them achieve a good nights sleep, it's the best quality, customer service is great, shipments are on time. There are a handful of reviews that are not positive with complaints about price.

Use code "HempJubilation" for 20% off sitewide

Five CBD Full Spectrum CBD+THC Oil

Five CBD is a unique brand that offers a true full-spectrum CBD product packed with everything that makes hemp authentic. 5:1 ratio of CBD to THC, CBN and CBC. (5 parts CBD to 1 part minor cannabinoids). All Five CBD products are made in the USA from authentic U.S. grown hemp.


  • Type of CBD: Full Spectrum
  • CBD potency: 50 mg CBD per serving
  • COA: Available on product page
  • Return Policy: 30-days 
  • Shipping: Free on all USA orders excluding chocolates 

CBD oil from Five CBD is offered in a variety of combinations. You get the choice of 3 different concentrations. The 1500mg tincture contains 50mg of CBD per serving. The 3000mg formula contains 100mg per serving and the 6000mg formula also contains 100mg of CBD per serving.

The difference between the 3000 and 6000 formula is that the 6000mg formula has a total of 2 fl. Ounces as opposed to 1 ounce. But the concentration is the same in both of these.

You also get the choice of 3 tasty flavors: Citrus, Mint Chocolate, and Lavender.

All Five CBD products are CGMP (Certified Current Good Manufacturing Practice) and U.S. Hemp Authority-Certified, 100% Natural, as well as Third-party Lab Tested. In other words, these products are about as natural, effective, and genuine as CBD products get.

The brand offers an admirable Veteran program for Veterans, First Responders and all Health Care Workers. Take 40% Off Your Entire Order.

They also offer a subscription plan with repeat delivery options of every 30 days and save 30% off your entire order. You can pause, skip or cancel anytime.

It seems that customers have great things to say about Five CBD in their reviews, like love it, great customer service, cannot say enough wonderful things about this five CBD tincture. There are a couple of reviews that are not so positive saying just okay, doesn't taste good at all.

How We Chose the Best CBD Oil for Pain

We compared some of the most popular CBD brands to find the best ones for pain available to buy online. We have thoroughly vetted each of the brands on our list based on their quality, efficacy and how transparent the company is with what's inside the bottle. Each product in this article:

  • Is made by a company that provides proof of third-party testing readily available on their website
  • Is made with hemp grown in the United States
  • Is free of heavy metals, pesticides, and molds, according to the COA
  • Contains no more than 0.3 percent THC, according to the certificate of analysis (COA)

Additionally, we considered these factors when selecting the best CBD products for pain:

  • CBD potency or concentration (how much CBD a single dose provides)
  • Company certifications and Extraction method
  • Brand reputation and trustworthiness 
  • Customer reviews to filter out companies that have a terrible reputation
  • Customer service quality to ensure you will get the best service when buying your CBD oil
  • Shipping, Return & Refund Policies
  • Affordable pricing, aiming to include quality 
  • Any warning letters from the FDA

What the Science Says: Studies on CBD & Pain

While there’s still a lot to learn about CBD, there are several clinical trials and research studies that have found that cannabinoids (CBD and THC, CBG, CBC, CBN) may play a crucial role in difficult to treat, neuropathic pain, inflammatory pain, migraines, arthritis pain, chronic, and acute pain management.

Here are some of the studies that are worth calling attention to that show the amazing role that CBD plays in reducing pain and minimizing its intensity.

  • One Cannabinoids and Pain 2018 study evaluated how well CBD works to relieve chronic pain. The review looked at studies conducted between 1975 and 2018. These studies examined various types of pain, including: fibromyalgia, neuropathic pain, and cancer pain. Based on these studies, researchers concluded that CBD was effective in the treatment of chronic pain in adults and didn’t cause negative side effects.
  • A 2018 generalized study, found that there is a growing body of evidence to suggest that cannabinoids are beneficial for pain and inflammation and that CBD will most likely become part of future developments in pharmaceutical and technological sciences.
  • A more recent 2020 study has found that CBD can help relieve chronic pain, improve sleep, and reduce inflammation in some circumstances.

While there is still a lot more to learn about CBD, the future looks promising with dozens of studies and trials thus far showing that CBD oil and other CBD products may be effective in treating pain and inflammation for short and long-term relief.

How to Use CBD Oil for Pain

One of the most common questions is how to use CBD oil for pain and what dosage should new users take. Since CBD oil is not a one-size-fits-all solution, it can be difficult to nail down exactly what the best recommended dose will be.

Decide if you want to take an unflavored or flavored tincture? Flavored tinctures are easier on the taste buds, while unflavored tinctures tend to be an acquired taste for some of us.

Now it’s time to figure out your dosage. It’s best to start with a smaller dosage and gradually increase it. This could mean starting with 10 to 30mg a day. After a week or so, increase this amount by 5mg. Continue this until you feel that it’s effectively treating your pain. Plus, this way you can use as little CBD as is needed.

Because if you feel that your pain is bearable at a lower dosage or with less frequent use, there’s no need to use more CBD. This is how you can stretch your supply to last longer and save money.

Fill up the dropper with your desired oil dosage then squeeze the oil under your tongue but do not swallow. Allow the oil to sit under your tongue for 30 to 60 seconds, then swallow the CBD oil.

For best results, never take CBD oil on an empty stomach. We suggest to schedule your CBD servings with your eating schedule in mind. A study by a team of researchers found the active effect of a cannabinoid product was four times higher when taken after a meal.

The best types of foods to eat before taking CBD oil are fatty acids. Foods like Meat, Eggs, Fish, Nuts, and Avocado.

Establish a routine to understanding how your body responds to CBD oil. While most people take their dosage in a single serving, you could try splitting your dosage into two or more servings throughout the day to find what's best for you.

Finding what's right for you requires patience and experimentation. CBD doesn't behave the same for everyone. But once you do find what works for you, repeat that every day to develop a consistent routine that your body can rely on. One thing our bodies thrive on is regularity.

And be sure to properly store your CBD oil products. Heat, light, and humidity can deteriorate your CBD. So keep your CBD somewhere cool, dark, dry, and secure (away from kids and pets!).


Our list of the best CBD oil for pain is by no means a comprehensive list of every safe and reputable CBD brand on the market.

Nevertheless, it is a list of reputable brands with transparent third party lab testing publicly available on their website, clean hemp sources, affordable pricing, and excellent track records with their customers—so you can trust that you’re getting the highest-quality, best CBD oil for pain out there.

Just as important though, is that many users of all age ranges, including elderly people, have experienced tons of success using CBD oil for pain management and pain relief. The brands positive reviews is confirmation of that.

However, it is worth noting that the Food and Drug Administration (FDA) doesn’t regulate CBD like drugs and supplements. If you have a medical condition, or if you take prescription medications, talk to your doctor before trying CBD oil. CBD does interact with certain medicines, particularly those with a grapefruit warning.

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